Can You Take Tramadol With Aleve ?

Aleve VS Tramadol?

Aleve Pills
Aleve Pills


  • Aleve (Naproxen) is effective for the short-term relief of pain and inflammation associated with arthritis, gout, menstruation, and tendonitis; however, like other NSAIDs, it has the potential to adversely affect the stomach or heart and increase bleeding tendency.
  • Prescribed for Back Pain, Ankylosing Spondylitis, Bursitis, Neck Pain, Tendonitis, Spondylolisthesis, Sciatica, Rheumatoid Arthritis, Radiculopathy, Period Pain, Pain, Osteoarthritis, Muscle Pain, Juvenile Rheumatoid Arthritis, Headache, Gout - Acute, Frozen Shoulder, Fever, Dysautonomia, Diffuse Idiopathic Skeletal Hyperostosis, Costochondritis, Chronic Myofascial Pain, Transverse Myelitis.
  • May also be prescribed off label for Aseptic Necrosis, Herniated Disk.
  • Prescription and OTC

Tramadol pills
Tramadol pills


  • Tramadol is a strong pain relief medicine effective for both general and nerve-related pain. Tramadol can cause dependence and use may be limited by side effects such as nausea and sedation. Pain-relieving effects or side effects may be altered in some people due to genetic variation or drug interactions.
  • Prescribed for Back Pain, Chronic Pain, Pain.
  • May also be prescribed off label for Anxiety, Depression, Fibromyalgia, Obsessive Compulsive Disorder, Restless Legs Syndrome, Syringomyelia, Vulvodynia.
  • Prescription only

Can You Take Tramadol With Aleve?

  • No drug interaction were found among naproxen and tramadol. This doesn't really mean no connections exist. Continuously counsel your pharmacist or physician.
  • However, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.
  • Different drugs that your chose medications communicate with
  • naproxen interfaces with in excess of 200 different medications.
  • tramadol cooperates with in excess of 300 different medications.
  • Connections between your chose medications and nourishment
  • No outcomes found - in any case, this doesn't really mean no collaborations exist. Continuously counsel with your PCP or drug specialist

Drug Interaction Classification

Drug Interaction Classification Checker
Drug Interaction Classification Checker

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult t determine. Always consult your healthcare provider before starting or stopping any medication.

  • Major

    Highly clinically significant. Maintain a strategic distance from mixes; the danger of the interaction exceeds the advantage.

  • Moderate

    Moderately clinically significant. Generally stay away from mixes; use it just under unique conditions.

  • Minor

    Minimally clinically significant. Limit hazard; evaluate chance and think about an elective medication, find a way to go around the cooperation chance and additionally establishment an observing arrangement.

  • Unknown

    No interaction data accessible.

    Tramadol and aleve cooperation goes under the class of unknown interaction. So you can take tramadol with aleve with no symptom and connection.

  • Doscussion

    Some studies shows demonstrated that tramadol decreased the amount of naproxen needed to maintain adequate pain relief in naproxen-responsive patients with painful OA of the knee. The addition of tramadol 200 mg/day allowed for a mean reduction of 78% in the daily dosage of naproxen without compromising pain relief. Fiftyeight percent of naproxen-responsive patients were able to discontinue naproxen with the addition of tramadol. . BUT In patients requiring NSAID therapy, the incidence of serious adverse events may be decreased if the NSAID can be used at the lowest effective dose BY USING TRAMADOL. The results of this study suggest that patients responding to higher doses of naproxen or potentially any NSAID may be able to reduce their risk of serious NSAID-induced adverse events by adding tramadol. This study demonstrated that by adding tramadol 200 mg/day to the regimen of patients with knee pain responsive to naproxen 1,000 mg/day, a significant reduction in the naproxen dosage could be achieved. Fifty-eight percent of patients could discontinue naproxen completely without compromising pain relief. Adding tramadol to the treatment regimen of patients with OA(osteo-arthritis) receiving higher doses of NSAIDs may ultimately allow a reduction in NSAID- related adverse events. Longer-term observations would be necessary to confirm this benefit.